Low water solubility and bioavailability limit the clinical application of drugs. Solubilizing agents, such as Mobil Composition of Matter Number 41 (MCM) as a drug carrier, can improve the water solubility of the drugs. In this study, PEGylated MCM nanoparticles were synthesised and loaded with fenbendazole, which is a potential anticancer drug, to improve its solubility and, as a result, its cytotoxicity effect against human prostate cancer PC-3 cells.

All data related to this study are contained within the article, "Esfahani, Maedeh Koohi Moftakhari, Alavi, Seyed Ebrahim, Cabot, Peter J., Islam, Nasrul, & Izake, Emad L. (2021) PEGylated Mesoporous Silica Nanoparticles (MCM-41): A Promising Carrier for the Targeted Delivery of Fenbenzadole into Prostrate Cancer Cells. Pharmaceutics, 13(10), Article number: 1605. https://eprints.qut.edu.au/214034/".