2023-06-30T09:50:12 n10811

Conjunctival and scleral thickness and ocular surface ultraviolet autofluorescence data

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Ultraviolet autofluorescence (UVAF) imaging is used to visualise ocular surface changes due to sunlight exposure and so is considered to be a biomarker for UV damage.  The conjunctival and scleral thicknesses of participants with and without ocular surface UVAF were measured to examine the UVAF associated tissue thicknesses. 

This dataset includes data collected and used for statistical analysis. It includes Ultraviolet Autofluorescence (UVAF) photographs and Ocular Coherence Tomography (OCT) images.

The presence of UVAF on the ocular surface was associated with significant differences in tissue thickness including thinner conjunctival epitheliums and thicker scleras but predominantly thickening of the conjunctival stroma. Participants were also classified into four groups according to the presence and absence of UVAF on both the temporal and nasal conjunctivas. It was noted that for those that had only nasal UVAF, the temporal conjunctival stroma was significantly thicker even without the presence of UVAF. Some participants with temporal UVAF had signs of pinguecula observed with slit lamp examination and some had OCT SLO enface imaging darkening. 

These findings highlight the potential of techniques other than slit lamp examination, including tissue thickness measurement and UVAF photography, in the detection of early UV-related changes to the ocular surface.

Access rights

The data which supports the findings of this study is available from corresponding author, Alyra Shaw, upon request. See 'Contacts' section for details.

Geographical area of data collection

153.317870,-26.996845 152.668523,-26.996845 152.668523,-27.767441 153.317870,-27.767441 153.317870,-26.996845


Rajasingam, P., Shaw, A., Davis, B. et al. The association between conjunctival and scleral thickness and ocular surface ultraviolet autofluorescence. Sci Rep 13, 7931 (2023). https://doi.org/10.1038/s41598-023-35062-2

Research areas

Ultraviolet autofluorescence (UVAF) imaging
Ocular surface UVAF
Vision science

Cite this collection

Rajasingam, Pryntha; Shaw, Alyra; Davis, Brett; Alonso-Caneiro, David; Hamwood, Jared; Collins, Michael; (2023): The association between conjunctival and scleral thickness and ocular surface ultraviolet autofluorescence. Queensland University of Technology. (Dataset) http://researchdatafinder.qut.edu.au/individual/n10811

Data file types

photographs (.jpeg), images (.bmp), Excel files (.xlsx)


Creative Commons Attribution 4.0 (CC-BY)


© Queensland University of Technology, 2023

Dates of data collection

From 2016 to 2017


Has association with
Brett Davis  (Researcher)
David Alonso-Caneiro  (Researcher)
Michael Collins  (Researcher)
Pryntha Rajasingam  (Researcher)
Has chief investigator
Alyra Shaw  (Researcher)


Date record created:
Date record modified:
Record status:
Published - Open Access