Mechanical testing of liver extracellular matrix-based hydrogels
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Porcine liver tissues were decellularized to obtain extracellular matrix using chemical detergent based protocols (Protocol I and Protocol II) over a period of 5 days. The matrix was functionalized with methacrylic anhydride to produce LivMA hydrogels that were photocrosslinked at different concentrations (0.5% and 0.75%) and crosslinking times (1,2,4 min). Mechanical testing of these hydrogels was conducted using compressive testing using 5848 Instron Microtester with a 5 N load cell.
The associated spreadsheet contains the raw data of the individual samples and the compiled data for all the different groups from both the protocols I and II.
Geographical area of data collection
kmlPolyCoords
153.015261,-27.452704
Publications
Ravichandran, A., Murekatete, B., Moedder, D. et al. Photocrosslinkable liver extracellular matrix hydrogels for the generation of 3D liver microenvironment models. Sci Rep 11, 15566 (2021).
http://dx.doi.org/https://doi.org/10.1038/s41598-021-94990-z
Research areas
Liver tissue engineering
ECM Hydrogels
Decellularization
Cite this collection
Ravichandran, Akhilandeshwari; Murekatete, Berline; Moedder, Denise; Meinert, Christoph; Bray, Laura; (2021): Mechanical testing of liver extracellular matrix-based hydrogels . Queensland University of Technology. (Dataset) https://doi.org/10.25912/RDF_1636687484822
Partner institution
Herston Biofabrication Institute, Metro North Health, Queensland
https://metronorth.health.qld.gov.au/herston-biofabrication-institute/
ARC Training Centre for Cell & Tissue Engineering Technologies
https://ctet.org.au/
Data file types
Microsoft Excel (.xlsx)
Licence
Copyright
© Queensland University of Technology, 2005.
Dates of data collection
From 2020-05-20 to 2020-12-23
Contacts
Name: Dr Akhilandeshwari Ravichandran
Phone: +61 469 026 385
Other
Date record created:
2021-08-27T14:30:33
Date record modified:
2021-11-12T14:08:09
Record status:
Published - Open Access