2021-11-12T14:08:09 n2518

Mechanical testing of liver extracellular matrix-based hydrogels

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Porcine liver tissues were decellularized to obtain extracellular matrix using chemical detergent based protocols (Protocol I and Protocol II) over a period of 5 days. The matrix was functionalized with methacrylic anhydride to produce LivMA hydrogels that were photocrosslinked at different concentrations (0.5% and 0.75%) and crosslinking times (1,2,4 min). Mechanical testing of these hydrogels was conducted using compressive testing using 5848 Instron Microtester with a 5 N load cell.

The associated spreadsheet contains the raw data of the individual samples and the compiled data for all the different groups from both the protocols I and II.

Geographical area of data collection

kmlPolyCoords
153.015261,-27.452704

Publications

Ravichandran, A., Murekatete, B., Moedder, D. et al. Photocrosslinkable liver extracellular matrix hydrogels for the generation of 3D liver microenvironment models. Sci Rep 11, 15566 (2021). http://dx.doi.org/https://doi.org/10.1038/s41598-021-94990-z

Research areas

Liver tissue engineering
ECM Hydrogels
Decellularization

Cite this collection

Ravichandran, Akhilandeshwari; Murekatete, Berline; Moedder, Denise; Meinert, Christoph; Bray, Laura; (2021): Mechanical testing of liver extracellular matrix-based hydrogels . Queensland University of Technology. (Dataset) https://doi.org/10.25912/RDF_1636687484822

Partner institution

Herston Biofabrication Institute, Metro North Health, Queensland https://metronorth.health.qld.gov.au/herston-biofabrication-institute/
ARC Training Centre for Cell & Tissue Engineering Technologies https://ctet.org.au/

Data file types

Microsoft Excel (.xlsx)

Licence


Creative Commons Attribution 4.0 (CC-BY)
http://creativecommons.org/licenses/by/4.0/

Copyright

© Queensland University of Technology, 2005.

Dates of data collection

From 2020-05-20 to 2020-12-23

Connections

Has association with
Laura Bray  (Researcher)
Has chief investigator

Contacts

Other

Date record created:
2021-08-27T14:30:33
Date record modified:
2021-11-12T14:08:09
Record status:
Published - Open Access