2021-09-23T11:41:02 n33486

Antibacterial Albumin-Tannic Acid Coatings for Scaffold-Guided Breast Reconstruction

Viewed: 21

The dataset contains the surface characterisation of 3D-printed non-porous and micro-porous medical-grade polycaprolactone (mPCL) scaffolds via Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), and microcomputed tomography. In addition, the mechanical properties of these scaffolds were tested by applying uniaxial compression using an Instron model 5848. 

Human serum albumin (HSA) and tannic acid (TA) were immobilised onto the surface of micro-porous mPCL scaffolds. Herein, we include the surface characterisation of the modified surfaces using FTIR, XPS, and fluorescein 5(6)-isothiocyanate (FITC)-labelling. Finally, the antibacterial in vitro efficacy of HSA/TA-coated scaffolds was assessed in a 2D zone of inhibition assay against S. aureus and P. aeruginosa. Nevertheless, since 2D zone of inhibition assays do not fully represent the interactions of coated scaffolds with bacteria in a realistic in vivo environment, a 3D in vitro assay was designed in order to investigate the antibacterial properties of coated scaffolds against S. aureus in suspension.

The data is available under the 'Access the data' link, as well as in the Supplementary Material section of the article 'Antibacterial Albumin-Tannic Acid Coatings for Scaffold-Guided Breast Reconstruction'. 

Geographical area of data collection

kmlPolyCoords
153.030263,-27.477617

Publications

Cometta, Silvia, Bock, Nathalie, Suresh, Sinduja, Dargaville, Tim R., & Hutmacher, Dietmar W. (2021) Antibacterial Albumin-Tannic Acid Coatings for Scaffold-Guided Breast Reconstruction. Frontiers in Bioengineering and Biotechnology, 9, Article number: 638577. https://eprints.qut.edu.au/210248/

Research areas

Biomedical engineering
Biochemistry and cell biology
Other biological sciences
Regenerative medicine (incl. stem cells)
Medical physiology

Cite this collection

Cometta, Silvia; Bock, Nathalie; Suresh, Sinduja; Dargaville, Tim R.; Hutmacher, Dietmar W. (2021): Antibacterial Albumin-Tannic Acid Coatings for Scaffold-Guided Breast Reconstruction. Frontiers. Collection. https://doi.org/10.3389/fbioe.2021.638577.s001

Data file types

.xlsx .pzf .jpg .tif

Licence


Creative Commons Attribution 4.0 (CC-BY)
http://creativecommons.org/licenses/by/4.0/

Copyright

© Queensland University of Technology, 2021.

Dates of data collection

From 2019-03-25 to 2021-02-28

Connections

Has association with
Nathalie Bock  (Researcher)
Tim Dargaville  (Researcher)
Has chief investigator
Dietmar Hutmacher  (Researcher)

Contacts

Name: Distinguished Professor Dietmar Hutmacher
Phone: +61 7 3138 6077

Other

Date record created:
2021-08-17T13:58:45
Date record modified:
2021-09-23T11:41:02
Record status:
Published - Open Access