2022-12-20T11:19:10 n41070

Conserved FimH mutations in the global Escherichia coli ST131 multi-drug resistant lineage weaken interdomain interactions and alter adhesin function

Viewed: 28

This dataset contains: raw bacterial colony forming unit count in the bacterial cell adhesion and invasion experiments described in the article.

Representative input files for the MD simulations and the resulting trajectories are available on Zenodo 

Raw data files of in vitro assays.

Geographical area of data collection

kmlPolyCoords
149.118324,-35.281253
kmlPolyCoords
153.028365,-27.478521

Publications

Qin, Jilong, Wilson, Katie A., Sarkar, Sohinee, Heras, Begoña, O'Mara, Megan L., & Totsika, Makrina (2022) Conserved FimH mutations in the global Escherichia coli ST131 multi-drug resistant lineage weaken interdomain interactions and alter adhesin function. Computational and Structural Biotechnology Journal, 20, pp. 4532-4541. https://eprints.qut.edu.au/236756/

Research areas

Cell infection
Cell adhesion
Bacteriology
Cell invasion

Cite this collection

Qin, Jilong; (2022): Conserved FimH mutations in the global Escherichia coli ST131 multi-drug resistant lineage weaken interdomain interactions and alter adhesin function. Queensland University of Technology. (Dataset) http://researchdatafinder.qut.edu.au/individual/n41070

Related information

Wilson, K.A., & O'Mara, M.L. (2022). Computational Data for Weaker interdomain interactions in FimH30 from multidrug-resistant Escherichia coli ST131 mediate longer lasting interactions with mannose and enhanced adhesin function [Data set]. Zenodo. https://doi.org/10.5281/zenodo.6324277

Partner institution

Australian National University https://www.anu.edu.au/research/our-research

Data file types

Online data link, and .pzfx file (GraphPad Prism)

Licence


Creative Commons Attribution-NonCommercial-No Derivatives 4.0 (CC-BY-NC-ND)
http://creativecommons.org/licenses/by-nc-nd/4.0/

Copyright

© Queensland University of Technology, 2021.

Dates of data collection

From 01-03-2017 to 01-12-2021

Connections

Has chief investigator
Makrina Totsika  (Researcher)

Contacts

Name: Dr Qin Jilong

Other

Date record created:
2022-10-07T15:48:09
Date record modified:
2022-12-20T11:19:10
Record status:
Published - Open Access