2017-01-20T15:42:13 n7701

Table of model parameters: Towards a quantitative theory of epidermal calcium profile formation in unwounded skin

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This data consists of a table containing model parameters obtained from experimental literature, with subsequent calculations performed as necessary (as described in Supporting Information, Text S1, in the associated publication). All data used in this work is either provided in Table 1 or extracted from figures published in references 26 and 28 (Mauro et al. 1998; Behne et al. 2003) using the program xyExtract.

The research conducted forms part of a PhD thesis, "Mathematical Models of Calcium and Tight Junctions in Normal and Reconstructed Epidermis." Proposed and mathematically examined was a theory of calcium profile formation in unwounded mammalian epidermis based on: changes in keratinocyte proliferation, fluid and calcium exchange with the extracellular fluid during these cells' passage through the epidermal sub-layers, and the barrier functions of both the stratum corneum and tight junctions localised in the stratum granulosum. Using this theory, a mathematical model was developed that predicts epidermal sub-layer transit times, partitioning of the epidermal calcium gradient between intracellular and extracellular domains, and the permeability of the tight junction barrier to calcium ions.

Geographical area of data collection

kmlPolyCoords
153.552920,-26.777500 152.452799,-26.777500 152.452799,-28.037280 153.552920,-28.037280 153.552920,-26.777500

Publications

Adams, Matthew P., Mallet, Daniel G., & Pettet, Graeme J. (2015) Towards a quantitative theory of epidermal calcium profile formation in unwounded skin. PLOS ONE, 10(1), e0116751. http://dx.doi.org/10.1371/journal.pone.0116751/

Research areas

unwounded epidermis
porous medium
keratinocytes
mathematical model
mammalian
calcium profile
epidermal structure

Cite this collection

Adams,Matthew; Mallet,Dann; Pettet,Graeme. (2015): Table of model parameters: Towards a quantitative theory of epidermal calcium profile formation in unwounded skin. [Queensland University of Technology]. https://doi.org/10.4225/09/5881a2ea3e527

Related information

Matthew Adams, Researcher Profile http://researchers.uq.edu.au/researcher/3058
Matthew Adams, ePrints publications http://eprints.qut.edu.au/view/person/Adams,_Matthew.html

Licence


Creative Commons Attribution 4.0 (CC-BY)
http://creativecommons.org/licenses/by/4.0/

Copyright

© 2015 Adams et al.

Dates of data collection

From 2014 to 2014

Connections

Has association with
Dann Mallet  (Researcher)
Graeme Pettet  (Researcher)

Contacts

Name: Matthew Adams

Other

Date record created:
2015-02-03T10:45:08
Date record modified:
2017-01-20T15:42:13
Record status:
Published - Open Access