2022-08-16T10:18:17 n12166

PEGylated Mesoporous Silica Nanoparticles (MCM-41): A Promising Carrier for the Targeted Delivery of Fenbendazole into Prostrate Cancer Cells

Viewed: 31

Low water solubility and bioavailability limit the clinical application of drugs. Solubilizing agents, such as Mobil Composition of Matter Number 41 (MCM) as a drug carrier, can improve the water solubility of the drugs. In this study, PEGylated MCM nanoparticles were synthesised and loaded with fenbendazole, which is a potential anticancer drug, to improve its solubility and, as a result, its cytotoxicity effect against human prostate cancer PC-3 cells.

All data related to this study are contained within the article, "Esfahani, Maedeh Koohi Moftakhari, Alavi, Seyed Ebrahim, Cabot, Peter J., Islam, Nasrul, & Izake, Emad L. (2021) PEGylated Mesoporous Silica Nanoparticles (MCM-41): A Promising Carrier for the Targeted Delivery of Fenbenzadole into Prostrate Cancer Cells. Pharmaceutics, 13(10), Article number: 1605. https://eprints.qut.edu.au/214034/".

Geographical area of data collection

kmlPolyCoords
153.317870,-26.996845 152.668523,-26.996845 152.668523,-27.767441 153.317870,-27.767441 153.317870,-26.996845

Publications

Esfahani, Maedeh Koohi Moftakhari, Alavi, Seyed Ebrahim, Cabot, Peter J., Islam, Nazrul, & Izake, Emad L. (2021) PEGylated Mesoporous Silica Nanoparticles (MCM-41): A Promising Carrier for the Targeted Delivery of Fenbendazole into Prostrate Cancer Cells. Pharmaceutics, 13(10), Article number: 1605. https://eprints.qut.edu.au/214034/

Research areas

Biotechnology
Nanotechnology
Biomaterials

Cite this collection

Koohi Moftakhari Esfahani, Maedeh; Alavi, Seyedebrahim; J. Cabot, Peter; Islam, Nazrul; L. Izake, Emad; (2022): PEGylated Mesoporous Silica Nanoparticles (MCM-41): A Promising Carrier for the Targeted Delivery of Fenbendazole into Prostrate Cancer Cells. Queensland University of Technology. (Dataset) http://researchdatafinder.qut.edu.au/individual/n12166

Licence


Creative Commons Attribution 4.0 (CC-BY)
http://creativecommons.org/licenses/by/4.0/

Copyright

© Maedeh Koohi Moftakhari Esfahani, 2022.

Dates of data collection

From 2020-07-01 to 2021-08-01

Connections

Has association with
Nazrul Islam  (Researcher)

Contacts

Name: Mrs Maedeh Koohi Moftakhari Esfahani

Other

Date record created:
2022-07-23T20:31:32
Date record modified:
2022-08-16T10:18:17
Record status:
Published - Open Access