2021-11-25T12:36:58 n15927

Imaging prostate tissue lipids using isomer-resolved mass spectrometry

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Data sets associated with the main text figures and supplementary information for the Fronteirs in Endocrinology publication "Isomer-Resolved Imaging of Prostate Cancer Tissues Reveals Specific Lipid Unsaturation Profiles Associated With Lymphocytes and Abnormal Prostate Epithelia".

Data has been divided into primary folders, with labels referring to the relevant main/SI figure. Data folders will include raw data files generated by the analytical instruments (see METHODS section within the publication for more information), text files of specific data extracts,  and image file types for microscopy and MALDI-MSI.

Geographical area of data collection

1) QUT - Gardens Point Campus, P Block, Brisbane City, QLD 4000, Australia.
3) Universiteitssingel - 50, 6229 ER Maastricht, Netherlands.
2) TRI Princess Alexandra Hospital, Brisbane, QLD 4000, Australia.


Tousignant, Kaylyn D, Rockstroh, Anja, Poad, Berwyck L J, Talebi, Ali, Young, Reuben S E, Taherian Fard, Atefeh, Gupta, Rajesh, Zang, Tuo, Wang, Chenwei, Lehman, Melanie L, Swinnen, Johan V, Blanksby, Stephen J, Nelson, Colleen C, & Sadowski, Martin C (2020) Therapy-induced lipid uptake and remodeling underpin ferroptosis hypersensitivity in prostate cancer. Cancer & Metabolism, 8, Article number: 11. https://eprints.qut.edu.au/202211/
Paine, Martin, Poad, Berwyck, Eijkel, Gert, Marshall, David, Blanksby, Stephen, Heeren, Ron, & Ellis, Shane (2018) Mass spectrometry imaging with isomeric resolution enabled by ozone-induced dissociation. Angewandte Chemie (International Edition), 57(33), pp. 10524-10530. https://eprints.qut.edu.au/120319/
Young, Reuben S.E., Bowman, Andrew P., Williams, Elizabeth D., Tousignant, Kaylyn D., Bidgood, Charles L., Narreddula, Venkateswara R., Gupta, Rajesh, Marshall, David L., Poad, Berwyck L.J., Nelson, Colleen C., Ellis, Shane R., Heeren, Ron M.A., Sadowski, Martin C., & Blanksby, Stephen J. (2021) Apocryphal FADS2 activity promotes fatty acid diversification in cancer. Cell Reports, 34(6), Article number: 108738. https://eprints.qut.edu.au/208094/
Poad, Berwyck, Marshall, David, Harazim, Eva, Gupta, Raj, Narreddula, Venkateswara Reddy, Young, Reuben, Duchoslav, Eva, Campbell, J., Broadbent, James, Cvacka, Josef, Mitchell, Todd, & Blanksby, Stephen (2019) Combining charge-switch derivatization with ozone-induced dissociation for fatty acid analysis. Journal of the American Society for Mass Spectrometry, 30(10), pp. 2135-2143. https://eprints.qut.edu.au/131340/
Marshall, David, Criscuolo, Angela, Young, Reuben, Poad, Berwyck, Zeller, Martin, Reid, Gavin, Mitchell, Todd, & Blanksby, Stephen (2019) Mapping unsaturation in human plasma lipids by data-independent ozone-induced dissociation. Journal of the American Society for Mass Spectrometry, 30(9), pp. 1621-1630. https://eprints.qut.edu.au/130909/

Research areas

Isomer elucidation
Ozone-induced Dissociation
Cell Biology
Mass Spectrometry
Molecular Imaging
Prostate cancer

Cite this collection

Young, Reuben; Claes, Britt; Bowman, Andrew; Williams, Elizabeth; Shepherd, Benjamin; Perren, Aurel; Poad, Berwyck; Ellis, Shane; Heeren, Ron; Sadowski, Martin; Blanksby, Stephen; (2021): Imaging prostate tissue lipids using isomer-resolved mass spectrometry. Queensland University of Technology. (Collection) https://doi.org/10.25912/RDF_1625715878910

Partner institution

Translational Research Institute Australia https://www.tri.edu.au/translational-research-institute-australia

Data file types

Mass spec instrument files (.raw file folders) - to be used with Waters HDI or MassLynx software .txt files (tab delineated) with extracted data .fig files to be used with MatLab Image files (.png, .tif)


Creative Commons Attribution-NonCommercial-Share Alike 4.0 (CC-BY-NC-SA)


© Reuben S. E. Young, 2021.

Dates of data collection

From 2019-06-06 to 2021-06-18


Has chief investigator
Stephen Blanksby  (Researcher)


Name: Mr Reuben Young


Date record created:
Date record modified:
Record status:
Published - Open Access